| Stage 5: Belvedere Marittimo to Contursi Terme, 203km |
| 1. Pavel Brutt (Rus) Tinkoff Credit Systems | 5:04:52 |
| 2. Johannes Frohlinger (Ger) Gerolsteiner | at 0:04 |
| 3. Luis Felipe Laverde (Col) CSF Group Navigare | 0:10 |
| 4. Francisco Perez (Esp) Caisse d'Epargne | 0:25 |
| 5. Paolo Bettini (Ita) Quick Step | 0:31 |
| 6. Daniele Pietropolli (Ita) LPR Brakes |
| 7. Riccardo Ricco (Ita) Saunier Duval - Scott |
| 8. Franco Pellizotti (Ita) Liquigas |
| 9. Jussi Veikkanen (Fin) Française des Jeux |
| 10. Alberto Contador Velasco (Esp) Astana |
| 11. Enrico Gasparotto (Ita) Barloworld |
| 12. Morris Possoni (Ita) Team High Road |
| 13. Jurgen Van Den Broeck (Bel) Silence - Lotto |
| 14. Denis Menchov (Rus) Rabobank |
| 15. Emanuele Sella (Ita) CSF Group Navigare |
| 16. Andreas Kloden (Ger) Astana |
| 17. Davide Rebellin (Ita) Gerolsteiner |
| 18. Joaquin Rodriguez (Esp) Caisse d'Epargne |
| 19. Nicki Sorensen (Den) Team CSC |
| 20. Danilo Di Luca (Ita) LPR Brakes |
|
| 27. Christian Vande Velde (USA) Slipstream Chipotle p/b H30 |
| 35. Levi Leipheimer (USA) Astana | all s.t. |
| 107. Ryder Hesjedal (Can) Slipstream Chipotle p/b H30 | 3:03 |
| 110. Jason McCartney (USA) Team CSC | 3:18 |
| 111. Jonathan Patrick McCarty (USA) Slipstream Chipotle p/b H30 | s.t. |
| 116. Danny Pate (USA) Slipstream Chipotle p/b H30 | 13:27 |
|
| GC |
| 1. Franco Pellizotti (Ita) Liquigas | 21:46:49 |
| 2. Christian Vande Velde (USA) Slipstream Chipotle p/b H30 | at 0:01 |
| 3. Danilo Di Luca (Ita) LPR Brakes | 0:07 |
| 4. Morris Possoni (Ita) Team High Road | 0:08 |
| 5. Vincenzo Nibali (Ita) Liquigas | s.t. |
| 6. Nicki Sorensen (Den) Team CSC | 0:17 |
| 7. Kanstantsin Siutsou (Blr) Team High Road | 0:18 |
| 8. Paolo Savoldelli (Ita) LPR Brakes | 0:19 |
| 9. Andrea Noe (Ita) Liquigas | 0:22 |
| 10. Daniele Bennati (Ita) Liquigas | 0:24 |
|
| 21. Levi Leipheimer (USA) Astana | 0:40 |
| 81. Ryder Hesjedal (Can) Slipstream Chipotle p/b H30 | 5:26 |
| 141. Jason McCartney (USA) Team CSC | 22:40 |
| 175. Jonathan Patrick McCarty (USA) Slipstream Chipotle p/b H30 | 34:38 |
| 180. Danny Pate (USA) Slipstream Chipotle p/b H30 | 37:54 |
